Pravadoline is a nonacidic, aminoalkylindole analgesic agent that inhibits cyclooxygenase.1 Like NSAIDs, pravadoline inhibits prostaglandin synthesis (IC50 = 5 μM in mouse brain microsomes) and displays antinociceptive activity (ED50 = 26 mg/kg in an acetylcholine-
Chemical and physical data
Molar mass 378.46 g/mo
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