4F-PHP goes by the formal and systematic IUPAC name of 1-(4-fluorophenyl)-2-(pyrrolidin-1-yl)hexan-1-one, it has a relative molar mass of 263.35 grams and an empirical formula of C16H22FNO.
4F-PHP may also go by the name 4-fluro-pyrrolidinohexiophenone. It is an analogue of the compound alpha-pyrrolidinohexiophenone with 4F-PHP distinguished from its parent compound by having the aromatic ring fluorinated in the para position.
Fluorination of drug compounds can sometimes increase bioavailability and lipophilicity and the highly electronegative character of fluorine can change the topographical charge of the molecule interfering with metabolism and giving the compound a longer half life.
The electronegative fluorine atom should make the carbonyl less polar and reduce reactivity of the compound.
4F-PHP belongs to the class of chemicals known as substituted cathinones.
The substituted cathinones are a series of compounds which feature a phenethylamine backbone with a ketone at the beta carbon and various alkyl moieties substituted at the alpha carbon adjacent to the amine. 4F-PVP and α-PHP have a butyl substitute at the alpha carbon. This confers increased lipohpilicity to these particular cathinones. The nitrogen itself is transformed in to a pyrrolidine moiety as it forms a five member ring with four other carbons.
Effects of 4F- PHP
There are many other cathinone compounds with a similar structure as that of 4F- PHP. The similar compounds are known to cause many stimulatory effects upon consumption. Some of cathinone compounds have been reported to act as entactogens and some have been studied to have a potential of inducing euphorbia state. As already mentioned, the class of cathinones comes from a plant called Khat. This plant has been in use by many indigenous people who have reported the compound to cause some desired pleasant stimulatory effect on the person consuming this drug.
The substituted cathinone has a short time of human usage. In the last 15 years, the first compounds being used were mephedrone and methylone. These compounds were present online and thus received worldwide popularity. The reported effects of these drugs were the same as that of the initial psychoactives like amphetamine, MDMA and the cocaine. The unverifiable and subjective reports are present online which suggest that this compound is really strong and helps in inducing stimulation, rush and euphorbia. However, still the research is in phase and nothing can be said about the authenticity of the reported effects of this chemical. There can be less, or more severe effects of 4F- PHP and it is better not to start using this chemical before it is regarded as safe for human consumption by the scientists and researchers.
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