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4-HO-MET (4-hydroxy-N-methyl-N-ethyltryptamine, metocin, or methylcybin), is a lesser-known psychedelic drug. It is a structural− and functional analog of psilocin as well as the 4-hydroxyl analog of methylethyltryptamine (MET)
4-HO-MET (4-hydroxy-N-methyl-N-ethyltryptamine, metocin, or methylcybin), is a lesser-known psychedelic drug. It is a structural− and functional analog of psilocin as well as the 4-hydroxyl analog of methylethyltryptamine (MET). 4-ho-met vendor, Canada, pellets, Erowid,4 ho met psychonaut
4-HO-MET was first synthesized by Alexander Shulgin. In his book TiHKAL (Tryptamines I Have Known and Loved), the dosage is listed as 10-20 mg.2-ME-MAF
4-HO-MET produces a psilocin-like distortion of color, sound, and form. Very little data exists about the pharmacological properties, metabolism, and toxicity of 4-HO-MET. There have been no reports of deaths from 4-HO-MET, even though people have reported taking doses up to 150 mg, more than an order of magnitude above the effective dose.[unreliable source?]
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Find sources: “4-HO-MET” – news · newspapers · books · scholar · JSTOR (September 2017)
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Users report similar effects to psilocin, including mydriasis, closed and open eye visuals, euphoria, time dilation, and a general change in thought processes. 4-ACO-DMT
These effects occur in a wavelike pattern such as that of psilocybin with near-normal perception and high effect varying rapidly. The effects last for about 4–6 hours. 4-ho-met vendor, Canada, pellets, Erowid,4 ho met psychonaut.2-AI
4-HO-MET’s psychedelic effects are believed to come from its activity at the 5-HT2A receptor as a partial agonist. However, the role of these interactions and how they result in the psychedelic experience remains subject to on-going scientific investigation.
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